反应详情

温度

100 °C

In a 100 mL flask equipped with a reflux condenser, an inlet tube for hydrogen chloride gas and a thermometer were placed 2.1 g of 5-nitro-1-tetralone oxime and 40 mL of acetic acid. While bubbling hydrogen chloride gas, the mixture was heated at 100° C. for 4 hours with stirring by a stirring bar. After allowing the mixture to be cooled to room temperature, a precipitated 5-nitro-1-aminonaphthalene hydrochloride was collected by filtration and rinsed with a small amount of acetic acid. After drying in vacuo, 5-nitro-1-aminonaphthalene hydrochloride (1.0 g) was obtained. No naphthalene derivatives isomerized in the amino or nitro group were detected.

1. customWhile bubbling hydrogen chloride gas
2. temperatureto be cooled to room temperature
3. filtrationa precipitated 5-nitro-1-aminonaphthalene hydrochloride was collected by filtration
4. washrinsed with a small amount of acetic acid
5. customAfter drying in vacuo