HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → Ethyl 2-acetylamino-4-thiazoleacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | Ethyl 2-acetylamino-4-thiazoleacetate | HCID 3477732 | — |
Reaction Steps
Ethyl 2-(2-aminothiazol-4-yl)acetate was reacted with acetyl chloride in dichloroethane in the presence of triethylamine, and then the reaction mixture was worked up and purified in a usual manner to obtain ethyl 2-(2-acetylaminothiazol-4-yl)acetate as a colorless solid. MS: 229.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06740662B1 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-5d306a3a912545939136f2066be05193 |
| Source note | uspto-grants-2004_05 |