Ethyl 2-acetylamino-4-thiazoleacetate → (2-Acetylamino-thiazol-4-yl)-acetic acid

Participants

Reaction Steps

Ethyl 2-(2-acetylaminothiazol-4-yl)acetate was reacted in a mixture of ethanol-1M sodium hydroxide aqueous solution (1:1) at room temperature, and then the reaction mixture was worked up and purified in a usual manner to obtain 2-(2-acetylaminothiazol-4-yl)acetic acid as a colorless solid. MS: 201.

Provenance & Evidence