5-Formylsalicylic acid → n,n-Di-n-pentyl-2-hydroxy-5-formylbenzamide

HRID 1583031Notes

Reaction equation

HRID 1583031 reaction equation
C(C1C=C(C(O)=O)C(O)=CC=1)=O.[CH2:13]([N:18]([CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[C:19](=[O:30])[C:20]1[CH:25]=[C:24]([CH:26]=[O:27])[CH:23]=[CH:22][C:21]=1[O:28]C)[CH2:14][CH2:15][CH2:16][CH3:17]>>[CH2:31]([N:18]([CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:19](=[O:30])[C:20]1[CH:25]=[C:24]([CH:26]=[O:27])[CH:23]=[CH:22][C:21]=1[OH:28])[CH2:32][CH2:33][CH2:34][CH3:35]

Participants

3

Reactant 2

HCID 692265-Formylsalicylic acidHCID 22716819n,n-Di-n-pentyl-2-methoxy-5-formylbenzamide

Product 1

HCID 22716814n,n-Di-n-pentyl-2-hydroxy-5-formylbenzamide

Procedure

N,N-Di-n-pentyl-2-hydroxy-5-formylbenzamide was prepared from 5-formylsalicylic acid (250 mg, 1 eq) using the same procedure as for N,N-di-n-pentyl-2-methoxy-5-formylbenzamide. The product was obtained as pale brown oil (211 mg, 46%). 1H NMR (CDCl3) δ9.67 (s, 1H, O═C—H), 3.33 (m, 4H, NCH2).

Sources & evidence

ORD record
ord-22397d92933a4153b277eb5bb498330e
Source dataset
uspto-grants-2004_05
Patent number
US06740670B2

Reaction notes

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