HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Benzyloxy)-5-formylbenzoic acid → 2-(4-Trifluoromethylbenzyloxy)-5-formylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Benzyloxy)-5-formylbenzoic acid | HCID 969870 | — |
| Reactant | 4-Trifluoromethylbenzyl 2-(4-trifluoromethylbenzyloxy)-5-formylbenzoate | HCID 22716812 | — |
| Product | 2-(4-Trifluoromethylbenzyloxy)-5-formylbenzoic acid | HCID 22716787 | — |
Reaction Steps
2-(4-Trifluoromethylbenzyloxy)-5-formylbenzoic acid was prepared from 4-trifluoromethylbenzyl 2-(4-trifluoromethylbenzyloxy)-5-formylbenzoate (1.41 g, 1 eq) using the same procedure as for 2-benzyloxy-5-formylbenzoic acid. The product was obtained as a white powder (764 mg, 67%). 1H NMR (CDCl3) δ9.97 (s, 1H, O═C—H), 5.41 (s, 2H, CH2Ar).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06740670B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-535e9d2ab8d943a9bae3511824424b13 |
| Source note | uspto-grants-2004_05 |