Hydrochloric Acid → 7-Methyl-8-oxononanoic acid

HRID 1583075Notes

Reaction equation

[C:1]([C:4](C)([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([O:17]CC)=[O:16])[C:5](OCC)=O)(=[O:3])[CH3:2].Cl>>[CH3:5][CH:4]([C:1](=[O:3])[CH3:2])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([OH:17])=[O:16]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 22266834Diethyl 2-acetyl-2-methyloctanedioate

Product 1

HCID 222668237-Methyl-8-oxononanoic acid

Procedure

Hydrolysis of the crude diethyl 2-acetyl-2-methyl-suberate with concentrated hydrochloric acid gave a quantitative yield of 7-methyl-8-oxo-nonanoic acid.

Sources & evidence

ORD record: ord-23822b6d0b31460d99b287ef8c2d7e48
Source dataset: uspto-grants-2004_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06740755B2

Reaction notes

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