HRID1583171

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID107205

1,3-Cyclohexanedicarboxylic acid

C8H12O4

HCID22827650

未命名化合物

PRODUCTS

产物

反应SMILES：O=C(OCc1ccccc1)[C@H]1CCCN1C(=O)C1CCCC(C(=O)N2CCC[C@@H]2C(=O)OCc2ccccc2)C1

HCID53995729

未命名化合物

收率 70%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

Using General Procedure A with 5.6 g (23.2 mmol) D-Proline benzyl ester hydrochloride and 2.0 g (11.6 mmol) cyclohexane-1,3-dicarboxylic acid afforded, after flash chromatography (EtOAc), 4.4 g (70%) of the title compound as a colorless oil. MS m/e (%): 547 (M+H+, 100).

WORKUP

后处理

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