Bromine → 2-Bromo-4-(2-bromo-1,1,2-trifluoroethoxy)phenol

Participants

Reaction Conditions

Reaction Steps

7.2 g of bromine in 30 ml of chloroform were added dropwise, at 25° C., to a solution of 12.2 g of 4-(2-bromo-1,1,2-trifluoroethoxy)-phenol in 100 ml of anhydrous chloroform, and the mixture was stirred for 12 hours at 25° C. The solvent was removed, and the residue was distilled at 100° C./0.4 mbar to give 15.5 g of pure product.

Provenance & Evidence