Hydrogen Bromide → HCID 131714407, compound

HRID 1583389Notes

Reaction equation

HRID 1583389 reaction equation
[NH2:1][C:2]1[NH:3][C:4](=[O:12])[C:5]2[N+:6]([O-:11])=[CH:7][NH:8][C:9]=2[N:10]=1.[BrH:13]>>[BrH:13].[N:3]1[C:4](=[O:12])[C:5]2[C:9]([N:8]=[CH:7][N+:6]=2[O-:11])=[N:10][C:2]=1[NH2:1]

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 178508254HCID 178508254, compound

Product 1

HCID 131714407HCID 131714407, compound

Procedure

2-Amino-1,9-dihydro-6H-purin-6-one-7-oxide (50 mg, 0.29 mmol) was heated over a steam bath in 5 ml of 1.0M aqueous hydrobromic acid until it dissolved. The solution was filtered and cooled to room temperature for one hour and then allowed to stand at 5° C. overnight whereupon 33 mg of the hydrobromide salt of 2-amino-1,9-dihydro-6H-purin-6-one-7-oxide precipitated as white needles, mp >250° C.

Workup

  1. dissolutiondissolved
  2. filtrationThe solution was filtered
  3. customprecipitated as white needles, mp >250° C.

Sources & evidence

ORD record
ord-ea8c8ba1f92444038fa18470fd77173f
Source dataset
uspto-grants-1985_11
Patent number
US04551529

Reaction notes

Loading…