Methyl iodide → HCID 13557521, compound

Participants

Reaction Steps

A mixture of 2.2 g of 2,3-dimethyl-11-oxo-N-[4-(3-pyridinyl)butyl]-11H-pyrido[2,1-b]quinazoline-8-carboxamide and 10 ml of iodomethane was stirred at room temperature, under argon form 3 days. An orange gum was obtained after removal of the excess iodomethane which was crystallized from methanol to yield 2.3 g (77.2%) of orange crystals, m.p. 129° dec.

Provenance & Evidence