HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Pyrimidin-5-YL)hex-5-YN-1-OL → 6-(Pyrimidin-5-yl)hexan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Pyrimidin-5-YL)hex-5-YN-1-OL | HCID 13999752 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 6-(Pyrimidin-5-yl)hexan-1-ol | HCID 13557544 | 88.1% |
Reaction Steps
A solution of 25.3 g of 6-(5-pyrimidinyl)-5-hexyn-1-ol in 300 ml of isopropanol was hydrogenated over a total of 2.1 g of 10% palladium on carbon added in two portions. The residue was distilled to yield 22.8 g (88%) of 5-pyrimidinehexanol, bp 185°-196° C./0.35 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04551460 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-e0d021f8920d433ab995b2a0efadcffe |
| Source note | uspto-grants-1985_11 |