Pyridine → HCID 20260634, compound

HRID 1583424Notes

Reaction equation

HRID 1583424 reaction equation
[BrH:1].[Br:2][CH2:3][CH2:4][CH2:5][CH2:6][NH2:7].[N:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(O)C>[BrH:2].[Br-:1].[NH2:7][CH2:6][CH2:5][CH2:4][CH2:3][N+:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 1049PyridineHCID 241895104-Bromobutan-1-amine--hydrogen bromide (1/1)

Product 1

HCID 20260634HCID 20260634, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 17.4 g of 4-bromobutanamine hydrobromide and 6.0 ml (5.9 g) of pyridine in 75 ml of ethanol was heated under reflux for 18 hours. The reaction was cooled and the resulting solid was collected and recrystallized from ethanol to give 3.4 g (15%) of the analytical sample as colorless crystals, 1-(4-aminobutyl)pyridinium bromide hydrobromide mp 219° (decomposition).

Workup

  1. temperatureunder reflux for 18 hours
  2. temperatureThe reaction was cooled
  3. customthe resulting solid was collected
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-dc3179eb977e41668e8a54c6482d592a
Source dataset
uspto-grants-1985_11
Patent number
US04551460

Reaction notes

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