反应详情

A solution of 33.0 g. of 5-(3,4-diethoxybenzylidene)rhodanine and 23.4 g. of sodium hydroxide in 148 ml. of water was heated to 70° C. for 30 minutes. The solution was cooled and filtered and the filtrate was acidified by pouring into excess cold 10% hydrochloric acid. The precipitate was collected by filtration affording 25 g. of the desired subtitle intermediate which was used without further purification.

1. temperatureThe solution was cooled
2. filtrationfiltered
3. additionby pouring into excess cold 10% hydrochloric acid
4. filtrationThe precipitate was collected by filtration
5. customaffording 25 g
6. customof the desired subtitle intermediate which was used without further purification