Sodium Hydroxide → beta-(3,4-Diethoxyphenyl)-alpha-mercaptoacrylic acid

Participants

Reaction Steps

A solution of 33.0 g. of 5-(3,4-diethoxybenzylidene)rhodanine and 23.4 g. of sodium hydroxide in 148 ml. of water was heated to 70° C. for 30 minutes. The solution was cooled and filtered and the filtrate was acidified by pouring into excess cold 10% hydrochloric acid. The precipitate was collected by filtration affording 25 g. of the desired subtitle intermediate which was used without further purification.

Provenance & Evidence