Diethyl Ether → HCID 13533838, compound

HRID 1583857Notes

Reaction equation

HRID 1583857 reaction equation
[CH3:1][C:2]1[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH:3]=1.[BH4-].[Na+].CC[O:13][CH2:14][CH3:15]>>[CH2:14]([O:13][CH:7]1[CH2:6][CH:5]2[O:8][C:2]1([CH3:1])[CH2:3][CH2:4]2)[C:15]1[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 789134-Methylcyclohex-3-en-1-oneHCID 4311764Sodium borohydride

Product 1

HCID 13533838HCID 13533838, compound

Procedure

By procedures similar to those described in Embodiment 3, (+)-2-exo-hydroxy-1-methyl-7-oxabicyclo[2.2.1]heptane was prepared by treatment of 4-methyl-3-cyclohexen-1-one with sodium borohydride followed by epoxidation-cyclization and ether formation to yield the desired product, b.p. 100°-101° C. (0.2 mm).

Sources & evidence

ORD record
ord-6289b423f49b4888935f56bfb5308193
Source dataset
uspto-grants-1985_11
Patent number
US04554366

Reaction notes

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