6-Chloronicotinic acid → HCID 20257589, compound

HRID 1583991Notes

Reaction equation

HRID 1583991 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[CH:4][N:3]=1.[N:11]1([CH:16]([CH3:20])[CH2:17][CH2:18][NH2:19])[CH:15]=[CH:14][N:13]=[CH:12]1>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:19][CH2:18][CH2:17][CH:16]([N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)[CH3:20])=[O:8])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 792226-Chloronicotinic acidHCID 139528623-(1H-Imidazol-1-yl)butan-1-amine

Product 1

HCID 20257589HCID 20257589, compound

Procedure

When 6-chloronicotinic acid was reacted with 3-(1H-imidazol-1-yl)butanamine by the procedure of Example 20 the desired compound was obtained, mp 137°-139° C.

Sources & evidence

ORD record
ord-221badf5337d4677a89af7864c1f78e9
Source dataset
uspto-grants-1985_11
Patent number
US04555519

Reaction notes

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