HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → HCID 20257587, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Reactant | 1H-Imidazole-1-pentanamine | HCID 7138434 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20257587 | HCID 20257587 | 79.2% |
Reaction Steps
A mixture of 1.58 g of 6-chloronicotinic acid and 1.62 g of 1,1'-carbonyldiimidazole in 30 ml of tetrahydrofuran was stirred at room temperature for 3 hours. Then 1.52 g of 1H-imidazole-1-pentanamine was added. The procedure of Example 36 was followed to conclusion and gave 2.3 g of the compound of the Example as white crystals, mp 110°-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04555519 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-9d2fee5e288d4186b8186d194580de9b |
| Source note | uspto-grants-1985_11 |