HCID 15405501, compound → HCID 15405503, compound

HRID 1584079Notes

Reaction equation

HRID 1584079 reaction equation
[C:1]([O:4][CH2:5][C:6]1[O:11][C:10](C)(C)O[C:8](=[O:14])[C:7]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(=[O:3])[CH3:2].C=[N:22][C:23]([CH3:31])([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[CH3:24]>C1(C)C(C)=CC=CC=1>[C:1]([O:4][CH2:5][C:6]1[O:11][CH2:10][N:22]([C:23]([CH3:31])([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH3:24])[C:8](=[O:14])[C:7]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 15405501HCID 15405501, compoundHCID 15405502HCID 15405502, compound

Product 1

HCID 15405503HCID 15405503, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of 6-acetyloxymethyl-2,2-dimethyl-5-phenyl-2H,4H-1,3-dioxin-4-one (Compound No. 241, 5.0 g) and N-methylene-1-methyl-1-phenylethylamine (2.9 g) was dissolved in xylene (40 ml) and allowed to react by refluxing for 30 minutes. The reaction mixture was purified by silica gel chromatography to afford the captioned compound (yield 72%).

Workup

  1. customto react
  2. temperatureby refluxing for 30 minutes
  3. customThe reaction mixture was purified by silica gel chromatography

Sources & evidence

ORD record
ord-03531a126a914b15bba4f060b7254081
Source dataset
uspto-grants-1999_08
Patent number
US05932521

Reaction notes

Loading…