Hydrochloric Acid → HCID 178500032, compound

Participants

Reaction Steps

A solution of trans-4-imidazoleacrylic acid (20.0 g 145 mmol) in methanol (300 ml) was saturated with anhydrous HCl and the resulting solution was then refluxed for 90 min. After cooling to room temperature the solvent was removed in vacu to to give the title compound as a white solid: 1H NMR (CD3OD) d 3.80 (s, 3 H), 6.61 (d, J=16 Hz, 1 H), 7.60 (d, J=16 Hz, 1 H), 7.92, (s, 1 H), 9.05, (s, 1 H).

Provenance & Evidence