4-(Chloromethyl)-5-methyl-2-phenyl-1,3-oxazole → 5-[2-[4-(5-Methyl-2-phenyl-4-oxazolylmethoxy)-3-methoxyphenyl]ethyl]-2,4-oxazolidinedione

Participants

Reaction Steps

In substantially the same manner as in Working Example 9, 5-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2,4-oxazolidinedione was reacted with 4-chloromethyl-5-methyl-2-phenyloxazole to obtain 5-[2-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)-3-methoxyphenyl]ethyl]-2,4-oxazolidinedione, which was recrystallized from ethyl acetate-chloroform to give colorless prisms, m.p.194-195° C.

Provenance & Evidence