2,4-Oxazolidinedione → HCID 86754367, compound

HRID 1584325Notes

Reaction equation

HRID 1584325 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[O:12][CH2:13][CH2:14][N:15]([CH3:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=1)[CH:5]=[CH:6][CH:7]=O.[O:23]1[CH2:27][C:26](=[O:28])[NH:25][C:24]1=[O:29]>>[F:1][C:2]1[CH:3]=[C:4]([CH2:5][CH2:6][CH2:7][N:25]2[C:26](=[O:28])[CH2:27][O:23][C:24]2=[O:29])[CH:9]=[CH:10][C:11]=1[O:12][CH2:13][CH2:14][N:15]([CH3:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=1

Participants

3

Reactant 2

HCID 973892,4-OxazolidinedioneHCID 73768319HCID 73768319, compound

Product 1

HCID 86754367HCID 86754367, compound

Procedure

In substantially the same manner as in Working Example 11, 3-fluoro-4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]cinnamaldehyde was condensed with 2,4-oxazolidinedione. The condensate was subjected to catalytic hydrogenation to yield 5-[3-[3-fluoro-4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]phenyl]propyl-2,4-oxazolidinedione, which was recrystallized from ethyl acetate-hexane to give colorless prisms, m.p.124-125° C.

Sources & evidence

ORD record
ord-0f902d4db8e34d5e99ee18964381156d
Source dataset
uspto-grants-1999_08
Patent number
US05932601

Reaction notes

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