Benzyl Bromide → HCID 21224475, compound

HRID 1584368Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH2:17](Br)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([O:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 10867928HCID 10867928, compound

Product 1

HCID 21224475HCID 21224475, compound

Procedure

In substantially the same manner as in Reference Example 92, ethyl 3-(3-hydroxy-4-methoxyphenyl)propionate was reacted with benzyl bromide to yield ethyl 3-(3-benzyloxy-4-methoxyphenyl)propionate. The product was recrystallized from hexane to give colorless needles, m.p.49.5-50.5° C.

Sources & evidence

ORD record: ord-f1f0737307f1436781be246cfe5f7520
Source dataset: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05932601

Reaction notes

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