Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Hydrogen iodide | HCID 24841 | — |
| Reactant | HCID 21223791 | HCID 21223791 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 86754354 | HCID 86754354 | — |
Reaction Steps
Combine 1-(t-butoxycarbonyl)-4-(1-(4-cyanobutyl)-1H-benzimidazol-2-yl)[1,4]diazepane (0.3 mmol) and dichloromethane (5 mL). Add aqueous 48% hydriodic acid solution (0.6 mmol). Heat to 40° C. After 6 hours, cool to ambient temperature dilute with diethyl ether (20 mL), and collect the solid to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05932571 |
|---|
| Source dataset | uspto-grants-1999_08 |
|---|
| ORD ID | ord-8b45892fc0c44ef28d58f8799c74d6df |
|---|
| Source note | uspto-grants-1999_08 |
|---|
