反应详情

In this example, inverse electron demand D-A reaction of acrolein with 3,4-tetrahydropyran is described. The procedure involves refluxing of 0.056 g of acrolein, 1.68 g of tetrahydropyran and 0.30 g of the catalyst prepared according to example 1 above in 10 ml of benzene at 60 (C 20 h. The catalyst was filtered off. After evaporation of solvent, the residue was chromatographed over silica gel column by eluting with 5% acetone/petroleum ether to give 0.12 g of endo adduct, 1,9-dioxabicyclo[4.4.05,10 ]dec-2-ene

1. customprepared
2. customC 20 h
3. filtrationThe catalyst was filtered off
4. customAfter evaporation of solvent
5. customthe residue was chromatographed over silica gel column
6. washby eluting with 5% acetone/petroleum ether