Ethanol → HCID 21219747, compound

Participants

Reaction Steps

23 [ml] of ethanol, 51.1 [g] of potassium hydroxide and 53.0 [g] of 2-acetoxy-1,4-di-n-butoxybenzene were added to 255 [ml] of water, and the mixture was reacted at 80° C. while stirring for 1 hour. After cooling the reaction liquor, it was neutralized and extracted twice with 200 [ml] of ethyl acetate. The extraction solution (i.e. the ethyl acetate solution) was washed with water, and concentrated by evaporating off the ethyl acetate as solvent under reduced pressure. Concentration of the extraction solution was continued until there was effectively no further evaporation of ethyl acetate (i.e., effectively no further ethyl acetate remained in the extraction solution). The separated crystals were filtered using filter paper, washed with a small amount of ethyl acetate, and dried to obtain 35.1 [g] of 2,5-di-n-butoxyphenol.

Provenance & Evidence