p-Chlorothiophenol → 1-[(4-Chlorophenyl)thio]-1-[(4-methoxyphenyl)hydrazono]-2-propanone

HRID 1584717Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1584717
Cl[C:2](=[N:6][NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1)[C:3](=[O:5])[CH3:4].[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([SH:23])=[CH:19][CH:18]=1.C(N(CC)CC)C>C(O)C>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([S:23][C:2](=[N:6][NH:7][C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)[C:3](=[O:5])[CH3:4])=[CH:19][CH:18]=1

Komponenten

5

Edukt 3

HCID 7815p-ChlorothiophenolHCID 8471TriethylamineHCID 2844936Propanehydrazonoyl chloride, N-(4-methoxyphenyl)-2-oxo-

Produkt 1

HCID 537286961-[(4-Chlorophenyl)thio]-1-[(4-methoxyphenyl)hydrazono]-2-propanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A suspension of 31.7 g (0.139 mol) of 1-chloro-1-[(4-methoxyphenyl)hydrazono]-2-propanone in 400 ml of ethanol was treated with 23.4 g (0.161 mole) of 4-chlorothiophenol followed by 23.4 ml of triethylamine. The suspension was heated at reflux for 2 hours and cooled. The resultant suspension was filtered and the precipitate was washed with 1 portion of cold ethanol. The solids were dried in vacuo to yield 1[(4-chlorophenyl)thio]-1-[(4-methoxyphenyl)hydrazono]-2-propanone, mp 111.5-113.5° C.

Aufarbeitung

  1. temperatureThe suspension was heated
  2. temperatureat reflux for 2 hours
  3. temperaturecooled
  4. filtrationThe resultant suspension was filtered
  5. washthe precipitate was washed with 1 portion of cold ethanol
  6. customThe solids were dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-d047013e2f51499995df62e4ef90e98c
Quelldatensatz
uspto-grants-1999_08
Patentnummer
US05935945

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