Potassium Carbonate → HCID 21220844, compound

Participants

Reaction Steps

A mixture of 2,2,2trifluoro-N-(7-methyl-benzofuran-5-yl)-acetamide (580 mg) and potassium carbonate (1.64 g) in methanol (25 ml) and water (2.5 ml) was heated at reflux for 2.5 hours. The residue was extracted with dichloromethane (3×25 ml) and the combined, dried (MgSO4) organic phase was evaporated in vacuo to give the title compound as a colourless oil (350 mg).

Provenance & Evidence