Hydrazine → HCID 21220632, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure of Example 47 but employing a solution of methyl 2-chloro-4-pentafluoroethylpyrimidine-5-carboxylate (0.55 g, 1.9 mmol; itself prepared by a reaction of methanol with 2-chloro-4-pentafluoroethylpyrimidine-5-carbonyl chloride (see Example 17)) and hydrazine (0.3 g, 9.4 mmol), resulting in a yield of 99% (0.54 g); 1HNMR (CDCl3) δ 8.87 (s, 1H), 7.09 (s, 1H), 3.92 (s, 3H), 1.7 (s, 2H).

Provenance & Evidence