Methylamine → HCID 59896603, compound

HRID 1585041Notes

Reaction equation

HRID 1585041 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9](SC)=[CH:10][N+:11]([O-:13])=[O:12])=[CH:4][CH:3]=1.[CH3:16][NH2:17]>CCO.CO>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9]([NH:17][CH3:16])=[CH:10][N+:11]([O-:13])=[O:12])=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 6329MethylamineHCID 85593012HCID 85593012, compound

Product 1

HCID 59896603HCID 59896603, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

In 25 ml of EtOH was dissolved 0.42 g (0.00171 mole) of 1-(6-chloro-3-pyridyl)amino-1-methylthio-2-nitroethylene, followed by addition of 0.2 g of a 40% solution of methylamine in methanol. The mixture was refluxed for 1.5 hours. The solvent was distilled off and the crystalline residue was washed with AcOEt and dried to recover 0.33 g of the title compound as white crystals.

Workup

  1. temperatureThe mixture was refluxed for 1.5 hours
  2. distillationThe solvent was distilled off
  3. washthe crystalline residue was washed with AcOEt
  4. customdried
  5. customto recover 0.33 g of the title compound as white crystals

Sources & evidence

ORD record
ord-5d9d54a5b511440a9b7c75ecfadc8866
Source dataset
uspto-grants-1999_08
Patent number
US05935981

Reaction notes

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