3-Aminopyridine → HCID 21221738, compound

HRID 1585135Notes

Reaction equation

HRID 1585135 reaction equation
[CH3:1][N:2]([CH3:19])[CH:3]1[CH2:18][CH2:17][C:6]2[O:7][C:8]3[CH:13]=[CH:12][C:11]([C:14]([OH:16])=O)=[CH:10][C:9]=3[C:5]=2[CH2:4]1.[NH2:20][C:21]1[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=1>>[N:23]1[CH:24]=[CH:25][CH:26]=[C:21]([NH:20][C:14]([C:11]2[CH:12]=[CH:13][C:8]3[O:7][C:6]4[CH2:17][CH2:18][CH:3]([N:2]([CH3:1])[CH3:19])[CH2:4][C:5]=4[C:9]=3[CH:10]=2)=[O:16])[CH:22]=1

Participants

3

Reactant 2

HCID 100093-AminopyridineHCID 21221573HCID 21221573, compound

Product 1

HCID 21221738HCID 21221738, compoundYield 44%

Procedure

Beginning with 0.17 gm (0.57 mMol) N,N-dimethyl-8- carboxy-1,2,3,4-tetrahydro-2-dibenzofuranamine and 0.06 gm (0.63 mMol) 3-aminopyridine, 0.083 gm (44%) of the title compound were recovered as an off-white foam by the procedure described in Example 25.

Sources & evidence

ORD record
ord-3224cc14ec474372aa7f474ef005ec91
Source dataset
uspto-grants-1999_08
Patent number
US05935992

Reaction notes

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