1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one → 1'-({6-Chloro-1-[(5-cyclopropyl-2-methyl-1,3-oxazol-4-yl)methyl]-1H-indol-3-yl}carbonyl)-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Reaction equation
[CH:29]1([c:32]2[c:33]([CH2:38][O:39][S:40]([CH3:41])(=[O:42])=[O:43])[n:34][c:35]([CH3:37])[o:36]2)[CH2:30][CH2:31]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][nH:8][c:9]2[cH:10]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][n:8]([CH2:38][c:33]3[c:32]([CH:29]4[CH2:30][CH2:31]4)[o:36][c:35]([CH3:37])[n:34]3)[c:9]2[cH:10]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b0dd8e18dea94eeb82670a5a49d0475b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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