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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 158551Generated: October 26, 2026

1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one → 1'-({6-Chloro-1-[(5-cyclopropyl-2-methyl-1,3-oxazol-4-yl)methyl]-1H-indol-3-yl}carbonyl)-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

https://huagongshe.com/reaction/158551

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657623—
ReactantMethanesulfonic acid 5-cyclopropyl-2-methyl-oxazol-4-ylmethyl esterHCID 86610240—
Product1'-({6-Chloro-1-[(5-cyclopropyl-2-methyl-1,3-oxazol-4-yl)methyl]-1H-indol-3-yl}carbonyl)-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657696—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b0dd8e18dea94eeb82670a5a49d0475b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)