Allyl Mercaptan → 3-Methoxy-6-allylthiopyridazine

Participants

Reaction Steps

1.15 g(0.05 mol) of metallic sodium was dissolved in 50 ml of absolute methanol and then mixed with 4.98 ml(0.05 mol) of allylmercaptan. To this mixture was added 7.23 g(0.05 mol) of 3-methoxy-6-chloropyridazine. The reaction solution was refluxed for 24 hours and then treated according to the same manner as Example 1 to obtain the title compound as a freezing pale white crystal.

Provenance & Evidence