Allyl Mercaptan → HCID 9837596, compound

HRID 1585989Notes

Reaction equation

HRID 1585989 reaction equation
[Na].[CH2:2]([SH:5])[CH:3]=[CH2:4].[CH3:6][O:7][C:8]1[C:17]2[CH2:16][CH2:15][CH2:14][CH2:13][C:12]=2[C:11](Cl)=[N:10][N:9]=1>CO>[CH3:6][O:7][C:8]1[C:17]2[CH2:16][CH2:15][CH2:14][CH2:13][C:12]=2[C:11]([S:5][CH2:2][CH:3]=[CH2:4])=[N:10][N:9]=1

Participants

5

Reactant 3

HCID 13367Allyl MercaptanHCID 5360545SodiumHCID 21217657HCID 21217657, compound

Product 1

HCID 9837596HCID 9837596, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.23 g(0.01 mol) of metallic sodium was dissolved in 30 ml of absolute methanol and then mixed with 0.93 ml(0.01 mol) of allylmercaptan. To this mixture was added 1.99 g(0.01 mol) of 1-methoxy-4-chloro-5,6,7,8-tetrahydro-phthalazine obtained from Preparation 6. The reaction solution was refluxed for one hour and then treated according to the same manner as Example 1 to obtain the title compound as a freezing pale white crystal.

Workup

  1. customobtained from Preparation 6
  2. temperatureThe reaction solution was refluxed for one hour
  3. additiontreated

Sources & evidence

ORD record
ord-ad18dbf9e5314c6f8be6c44b79580bc1
Source dataset
uspto-grants-1999_08
Patent number
US05942511

Reaction notes

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