Allyl Mercaptan → Pyridazine, 3-(2-propenylthio)-6-propoxy-

HRID 1585995Notes

Reaction equation

HRID 1585995 reaction equation
[Na].[CH2:2]([SH:5])[CH:3]=[CH2:4].[CH2:6]([O:9][C:10]1[N:11]=[N:12][C:13](Cl)=[CH:14][CH:15]=1)[CH2:7][CH3:8]>CO>[CH2:6]([O:9][C:10]1[N:11]=[N:12][C:13]([S:5][CH2:2][CH:3]=[CH2:4])=[CH:14][CH:15]=1)[CH2:7][CH3:8]

Participants

5

Reactant 3

HCID 13367Allyl MercaptanHCID 2528223-Chloro-6-propoxypyridazineHCID 5360545Sodium

Product 1

HCID 10330761Pyridazine, 3-(2-propenylthio)-6-propoxy-

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.15 g(0.05 mol) of metallic sodium was dissolved in 75 ml of absolute methanol and then mixed with 4.98 ml(0.05 mol) of allylmercaptan. To this mixture was added 8.63 g(0.05 mol) of 3-(n-propoxy)-6-chloropyridazine. The reaction solution was refluxed for 24 hours and then treated according to the same manner as Example 1 to obtain the title compound as a pale yellow oily residue.

Workup

  1. temperatureThe reaction solution was refluxed for 24 hours
  2. additiontreated

Sources & evidence

ORD record
ord-0a471fdb725042d98a5fc22967d9fb5c
Source dataset
uspto-grants-1999_08
Patent number
US05942511

Reaction notes

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