Water → HCID 178507829, compound

HRID 1586362Notes

Reaction equation

HRID 1586362 reaction equation
[N+:1]([C:4]1[C:9]([Cl:10])=[CH:8][C:7]([Cl:11])=[CH:6][C:5]=1[C:12]1[C:16]([Cl:17])=[CH:15][NH:14][N:13]=1)([O-])=O.O>C(O)(=O)C.[Fe]>[NH2:1][C:4]1[C:9]([Cl:10])=[CH:8][C:7]([Cl:11])=[CH:6][C:5]=1[C:12]1[C:16]([Cl:17])=[CH:15][NH:14][N:13]=1

Participants

5

Reactant 2

HCID 962WaterHCID 178526741HCID 178526741, compound

Product 1

HCID 178507829HCID 178507829, compoundYield 90%

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Conditions

Temperature
70 °C

Procedure

14.6 g (0.05 mol) of 3-(2-nitro-3,5-dichlorophenyl)-4-chloropyrazole, in solution in 200 ml of acetic acid, are introduced into a 500 ml, three-necked, round-bottomed flask. The solution is brought to 50° C. and 8.4 g (0.15 mol) of iron powder are introduced in portions. The reaction mixture is then kept stirring at 70° C. for 5 hours. After cooling, the reaction mixture is poured into 800 ml of water, filtered on sintered glass, rinsed with water and dried to lead to the production of a white solid (yield: 90%, M.p.: decomposition at 300° C.) of 3-(2-amino-3,5-dichlorophenyl)-4-chloropyrazole.

Workup

  1. customis brought to 50° C.
  2. temperatureAfter cooling
  3. filtrationfiltered on sintered glass
  4. washrinsed with water
  5. customdried

Sources & evidence

ORD record
ord-38ab9f4480924fcba2625ccc698d491b
Source dataset
uspto-grants-1999_08
Patent number
US05945382

Reaction notes

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