反应详情

A solution of 6.85 g (0.0185 mol) of 1-t-butoxycarbonylmethyl-4-chloro-3-(3,5-dichlorophenyl)pyrazole in 100 ml of trifluoroacetic acid is stirred for 16 h at room temperature. The reaction mixture is poured onto 300 cm3 of an ice/water mixture. The insoluble material is recovered by filtration, washed with heptane and dried. We obtained 5.65 g of 1-carboxymethyl-4-chloro-3-(3,5-dichlorophenyl)pyrazole, melting at 182° C.

1. filtrationThe insoluble material is recovered by filtration
2. washwashed with heptane
3. customdried