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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1586447Generated: October 31, 2026

1-(2-Hydroxyethyl)piperazine → 1-(4-Fluorobenzyl)-4-(2-Hydroxyethyl)Piperazine

https://huagongshe.com/reaction/1586447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant4-Fluorobenzyl chlorideHCID 9602—
Product1-(4-Fluorobenzyl)-4-(2-Hydroxyethyl)PiperazineHCID 693807—

Reaction Steps

The title compound was synthesized by using 2-(1-piperazinyl)ethanol and p-fluorobenzyl chloride according to the same process as in Preparation Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05945434
Source datasetuspto-grants-1999_08
ORD IDord-82a9b5df5a42495785edb6ec9460517d
Source noteuspto-grants-1999_08