Potassium Carbonate → HCID 178469029, compound

HRID 1586487Notes

Reaction equation

HRID 1586487 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][C:3]=1[CH2:13][S:14][C:15]1[NH:19][C:18]2[CH:20]=[CH:21][C:22]([O:24][CH3:25])=[CH:23][C:17]=2[N:16]=1.C(=O)([O-])[O-:27].[K+].[K+]>>[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][C:3]=1[CH2:13][S:14]([C:15]1[NH:19][C:18]2[CH:20]=[CH:21][C:22]([O:24][CH3:25])=[CH:23][C:17]=2[N:16]=1)=[O:27]

Participants

3

Reactant 2

HCID 11430Potassium CarbonateHCID 178469028HCID 178469028, compound

Product 1

HCID 178469029HCID 178469029, compound

Procedure

The title compound was prepared by the method of Example 3 using 557 mg of the title product of Example 72 instead of the title product of Example 2. The reaction mixture was passed three times through a column of potassium carbonate powder and concentrated in vacuo to dryness. Crystallization for acetonitrile gave 257 mg of the title compound. Anal. Calc'd. for C18H19N3O4S: C, 57.90; H, 5.13; N, 11.25; S, 8.59. Found: C, 57.63; H, 5.15; N, 11.32; S, 8.65.

Workup

  1. concentrationconcentrated in vacuo to dryness
  2. customCrystallization for acetonitrile

Sources & evidence

ORD record
ord-1264621e4cb24018ae78b1cdc93dbe94
Source dataset
uspto-grants-1999_08
Patent number
US05945425

Reaction notes

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