2,4-Dichloro-6-nitrophenol → 2-Amino-4,6-dichlorophenol

HRID 1586646Notes

Reaction equation

HRID 1586646 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([N+:9]([O-])=O)[C:3]=1[OH:12].[H][H]>[Pt]=O.CO>[NH2:9][C:4]1[CH:5]=[C:6]([Cl:8])[CH:7]=[C:2]([Cl:1])[C:3]=1[OH:12]

Participants

5

Reactant 2

HCID 118712,4-Dichloro-6-nitrophenolHCID 178418361HCID 178418361, compound

Product 1

HCID 106992-Amino-4,6-dichlorophenol

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 887MethanolSolvent

Procedure

The starting material, 2,4-dichloro-6-nitrophenol (260 g, 1 mole, 20% in water), was mixed with methanol (2 liters) and platinum oxide catalyst, and the resulting slurry was reacted with hydrogen at 4.2 kg/cm2 (60 psi) and room temperature.

Sources & evidence

ORD record
ord-dab98924dbbd47708dbb35d7c7b24aa1
Source dataset
uspto-grants-1993_06
Patent number
US05215925

Reaction notes

Loading…