Acetyl chloride → HCID 88483146, compound

HRID 1586893Notes

Reaction equation

HRID 1586893 reaction equation
[CH3:1][S+:2]([CH3:10])[C:3]1[CH:8]=[CH:7][C:6](O)=[CH:5][CH:4]=1.[CH3:11][O:12][S:13]([O-:16])(=[O:15])=[O:14].[C:17](Cl)(=[O:19])[CH3:18].C(N(CC)CC)C>C(#N)C>[CH3:11][O:12][S:13]([O-:16])(=[O:15])=[O:14].[CH3:1][S+:2]([CH3:10])[C:3]1[CH:8]=[CH:7][C:6]([CH2:18][C:17]([OH:19])=[O:12])=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 21915988(4-Hydroxyphenyl)(dimethyl)sulfanium methyl sulfate

Product 1

HCID 88483146HCID 88483146, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

In 30 ml of acetonitrile was dissolved 2.6 g of p-dimethylsulfoniophenol methylsulfate; and 0.8 ml of acetyl chloride and 1.4 ml of triethylamine were added dropwise thereto. The reaction mixture was filtered to remove the deposited triethylamine hydrochloride. The filtrate was concentrated under reduced pressure and the residue was crystallized by adding ether.

Workup

  1. filtrationThe reaction mixture was filtered
  2. customto remove the deposited triethylamine hydrochloride
  3. concentrationThe filtrate was concentrated under reduced pressure
  4. customthe residue was crystallized
  5. additionby adding ether

Sources & evidence

ORD record
ord-a30fac2c0be9422a945a8ab509f0949f
Source dataset
uspto-grants-1993_06
Patent number
US05216125

Reaction notes

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