p-Ethoxycarbonylbenzoyl chloride → HCID 19760190, compound

HRID 1586914Notes

Reaction equation

HRID 1586914 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]([CH3:12])[C:10](=[O:13])[CH2:9][CH2:8][CH2:7][C:6]=2[CH:14]=1.[CH2:15]([O:17][C:18]([C:20]1[CH:28]=[CH:27][C:23]([C:24](Cl)=[O:25])=[CH:22][CH:21]=1)=[O:19])[CH3:16]>>[CH3:12][N:11]1[C:5]2[CH:4]=[CH:3][C:2]([NH:1][C:24]([C:23]3[CH:27]=[CH:28][C:20]([C:18]([O:17][CH2:15][CH3:16])=[O:19])=[CH:21][CH:22]=3)=[O:25])=[CH:14][C:6]=2[CH2:7][CH2:8][CH2:9][C:10]1=[O:13]

Participants

3

Reactant 2

HCID 12276626p-Ethoxycarbonylbenzoyl chlorideHCID 197602587-Amino-1-methyl-1,3,4,5-tetrahydro-benzo[B]azepin-2-one

Product 1

HCID 19760190HCID 19760190, compound

Procedure

Analogous to Example 1, from 7-amino-2,3,4,5-tetrahydro-1-methyl-2-oxo-1H-1-benzazepine was reacted with p-ethoxycarbonylbenzoyl chloride to yield ethyl p-[(2,3,4,5-tetrahydro-1-methyl-2-oxo-1H-1-benzazepin-7-yl)carbamoyl]benzoate, m.p. 184°-185° C.

Sources & evidence

ORD record
ord-e4fbc81f2b694f19854e569f77b7d61f
Source dataset
uspto-grants-1993_06
Patent number
US05216148

Reaction notes

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