HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → 4'-Fluoro-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenecarboxanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid | HCID 227638 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 4'-Fluoro-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenecarboxanilide | HCID 19760311 | 60.7% |
Reaction Steps
In a manner analogous to Example 1, 2 g of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenecarboxylic acid and 1 g of 4-fluoroaniline were used to obtain 1.7 g of 4'-fluoro-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenecarboxanilide in colorless crystals, m.p. 163°-165° C. (from ethyl acetate/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05216153 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-0c027d06d4714b02901aab4a2fb95760 |
| Source note | uspto-grants-1993_06 |