Sulfuric Acid → HCID 15027117, compound

Participants

Reaction Steps

To a mixture of 0.1 g of aluminum lithium hydride and 2.5 ml of dry diethyl ether, 0.275 g of aluminum chloride and 2.5 ml of dry diethyl ether were added under stirring. To the resultant mixture, a solution of 0.48 g of the above-prepared 4-(3-trifluoromethylheptanoyl)anisole in 2.5 ml of diethyl ether, followed by heat-refluxing for 30 minutes. After the reaction, 5 ml of 6N-sulfuric acid was added to the reaction mixture, followed by extraction with diethyl ether. The ether layer was dried with anhydrous sodium sulfate, followed by distilling-off of the solvent to obtain 0.46 g of crude 4-(3-trifluoromethylheptyl)anisole

Provenance & Evidence