Acetone → HCID 22023996, compound

HRID 1587276Notes

Reaction equation

HRID 1587276 reaction equation
[OH:1][CH:2]([C:9]1[CH:22]=[CH:21][C:20]2[C:11](=[C:12]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[C:13]3[C:18]([N:19]=2)=[CH:17][CH:16]=[C:15]([CH:23]([OH:30])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:14]=3)[CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C[C:38]([CH3:40])=[O:39].[C:41](OC(=O)C)(=[O:43])[CH3:42]>CN(C)C1C=CN=CC=1.O>[C:41]([O:1][CH:2]([C:9]1[CH:22]=[CH:21][C:20]2[C:11](=[C:12]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[C:13]3[C:18]([N:19]=2)=[CH:17][CH:16]=[C:15]([CH:23]([O:30][C:38](=[O:39])[CH3:40])[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH:14]=3)[CH:10]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1)(=[O:43])[CH3:42]

Participants

6

Reactant 3

HCID 180AcetoneHCID 7918Acetic AnhydrideHCID 22023973HCID 22023973, compound

Product 1

HCID 22023996HCID 22023996, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 962WaterSolvent

Procedure

1 pbw of 2,7-bis(α-hydroxybenzyl)-9-phenylacridine is suspended in 4 pbw of acetone and heated for 1 hour under reflux with 0.8 pbw of acetic anhydride and 0.001 pbw of 4-dimethylaminopyridine. Water is then added to the mixture and the product is filtered off.

Workup

  1. temperatureheated for 1 hour
  2. filtrationthe product is filtered off

Sources & evidence

ORD record
ord-ee5bb72aac8e4c6bbd5dabd3ae8898f3
Source dataset
uspto-grants-1993_06
Patent number
US05217845

Reaction notes

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