4-Nitrophenol → Methyl 4-nitrophenyl carbonate

HRID 1587283Notes

Reaction equation

HRID 1587283 reaction equation
CN1C=CN=C1.Cl[C:8]([O:10][CH3:11])=[O:9].[CH:12]1[C:17]([N+:18]([O-:20])=[O:19])=[CH:16][CH:15]=[C:14]([OH:21])[CH:13]=1>CN(C1C=CN=CC=1)C>[C:8](=[O:9])([O:21][C:14]1[CH:15]=[CH:16][C:17]([N+:18]([O-:20])=[O:19])=[CH:12][CH:13]=1)[O:10][CH3:11]

Participants

5

Reactant 3

HCID 9804-NitrophenolHCID 13901-MethylimidazoleHCID 6586Methyl chloroformate

Product 1

HCID 86975Methyl 4-nitrophenyl carbonate

Reagents, catalysts & solvents 1

HCID 142844-(Dimethylamino)pyridineCatalyst

Procedure

N-methylimidazole and 4-(N,N-dimethylamino) pyridine (DMAP) are obtained from Aldrich Chemical Co. Methyl p-nitrophenyl carbonate is prepared from methyl chloroformate and p-nitrophenol.

Sources & evidence

ORD record
ord-bfc6d58c1acc49ecbd5bfa15a1adabea
Source dataset
uspto-grants-1993_06
Patent number
US05217866

Reaction notes

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