Water → HCID 10248656, compound

Participants

Reaction Steps

A solution of sodium hydroxide (0.36 g) in methanol (4.1 ml) was added to a solution of 2-(3-benzoylthioureido)-4,5-bis(4-methoxyphenyl)thiazole (4.3 g) and water (0.5 ml) in methanol (25 ml). The resulting mixture was stirred for 3 hours at 55°~60° C. The methanol was evaporated in vacuo and the residue was triturated with water. The precipitates were collected by filtration and dried to give 4,5-bis(4-methoxyphenyl)-2-thioureidothiazole (3.20 g).

Provenance & Evidence