Hydrogen Bromide → HCID 18652407, compound

Participants

Reaction Steps

1,3-Dihydro-1-(pyrrolidinylcarbonyl)methyl-3(R){[(α-methyl)benzyloxy-carbonyl]-amino}-5-phenyl-2H-1,4-benzodiazepin-2-one (109 mg) was dissolved in 10 ml of dry methylene chloride. The solution was cooled to 0° C. and saturated with hydrogen bromide gas. After 30 minutes the solvent and excess hydrogen bromide were removed under reduced pressure to give 147 mg of the title compound as a pale yellow solid.

Provenance & Evidence