Hydrochloric Acid → HCID 131717973, compound

Participants

Reaction Steps

A solution containing N-hydroxy-N,α-dimethyl-4'-[(1-methyl-1H-benzimidazol-2-yl)methoxy]-[1,1'-biphenyl]-4-acetamide (0.2 g, 0.48 mmol) in warm methanol (100 mL) is treated with 1M hydrogen chloride in diethyl ether (3 mL). The solution is concentrated under reduced pressure to a solid residue. This material is crystallized from a mixture of ethanol and diethyl ether to give 0.2 g (92.2%) of white crystalline product, m.p. 131° C. (dec.).

Provenance & Evidence