Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cannabinol → Tetrahydrocannabinol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cannabinol | HCID 2543 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Tetrahydrocannabinol | HCID 16078 | — |
반응 단계
Five ml of tetrahydrofuran containing 38.75 mg of a cannabinol derivative having the formula ##STR4## were added to the activated-LPS effluent, and the mixture was incubated for 18 hours at 22° C. in the dark. Two ml of a solution of 4.5 mg/ml NaBH4 in H2O were added, and the mixture was incubated for 30 minutes at room temperature. Unconjugated THC derivative was removed by dialysis for 2 days against frequent changes of water and for 2 days against 0.1M acetic acid, pH 3.5, to yield a THC-LPS conjugate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05219747 |
| 출처 데이터셋 | uspto-grants-1993_06 |
| ORD ID | ord-f9d9a26bcc7743459fc9ad768ac6d626 |
| 출처 메모 | uspto-grants-1993_06 |